Malegra 50 mg works by inhibiting PDE5 (phosphodiesterase type 5), an enzyme that breaks down cGMP, a chemical responsible for relaxing the smooth muscle in the blood vessels of the penis. By blocking PDE5, Sildenafil helps to increase levels of cGMP, allowing the blood vessels to relax and improve blood flow to the penis. This increased blood flow facilitates the ability to achieve and maintain an erection during sexual stimulation.

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